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Products Details
Product Description
– PROTAC ERα Y537S degrader-1 comprises a ubiquitin E3 ligase binding group, a linker and a protein binding group. PROTAC ERα Y537S degrader-1 extracts from patent WO2021143822, example 12. PROTAC ERα Y537S degrader-1 is an estrogen receptor-alpha (ERα) Y537S degrader[1].
Web ID
– HY-145071
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C46H49N5O6
References
– [1]Yang FL, et, al. Bicyclic imide derivative, preparation method thereof, and application thereof in medicine. WO2021143822A1.
CAS Number
– 2667598-05-0
Molecular Weight
– 767.91
SMILES
– O=C1C2=C(CN1C3C(NC(CC3)=O)=O)C=C(N4CCN(CC4)CC5CCN(C6=CC=C([C@]7([H])C8=CC=C(O)C=C8CC[C@]7([H])C9=CC=CC=C9)C=C6)CC5)C%10=C2OCO%10
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Estrogen Receptor/ERR;PROTACs
Pathway
– PROTAC;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
