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Losmapimod
Price range: 48 CAD through 1,550 CAD
Products Details
Product Description
– Losmapimod (GSK-AHAB) (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).
Web ID
– T2277
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H26FN3O2
Citations
– 1. Zhang X, Yan F, Tang K, et al. Identification of a clinical compound losmapimod that blocks Lassa virus entry. Antiviral Research. 2019 Apr 4;167:68-77
2. Li M, Wang Z, Fu S, et al.Taurine reduction of injury from neutrophil infiltration ameliorates Streptococcus uberis-induced mastitis.International Immunopharmacology.2023, 124: 111028.
3. Machine learning–enabled virtual screening indicates the anti-tuberculosis activity of aldoxorubicin and quarfloxin with verification by molecular docking, molecular dynamics simulations, and biological evaluations
References
– Willette RN, et al. J Pharmacol Exp Ther. 2009, 330(3), 964-970.
CAS Number
– 585543-15-3
Molecular Weight
– C22H26FN3O2
Compound Purity
– 0.9989
SMILES
– CC=1C(=CC(C(NC2CC2)=O)=CC1F)C3=CC=C(C(NCC(C)(C)C)=O)C=N3
Pathway
– Autophagy|||MAPK
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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