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CHM-1
Price range: 48 CAD through 819 CAD
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– CHM-1 is an inducer of apoptosis, and displays potent antitumor ability in human hepatocellular carcinoma by activation of Cdc2 kinase activity. CHM-1 inhibits tubulin polymerization in vitro and in vivo.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T22661
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C16H10FNO3
References
– Liu CW, et al. CHM-1, a novel microtubule-destabilizing agent exhibits antitumor activity via inducing the expression of SIRT2 in human breast cancer cells. Chem Biol Interact. 2018 Jun 1;289:98-108.
CAS Number
– 154554-41-3
Molecular Weight
– C16H10FNO3
Compound Purity
– 1
SMILES
– O=C1C2=C(NC(=C1)C3=C(F)C=CC=C3)C=C4C(=C2)OCO4
Target
– ALK|||TGF-beta/Smad|||PAI-1
Pathway
– Cytoskeletal Signaling|||Apoptosis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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