Laduviglusib trihydrochloride
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Laduviglusib trihydrochloride

SKU T22657-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 58 CAD through 2,384 CAD

Products Details

Product Description

– Laduviglusib trihydrochloride (CT99021 trihydrochloride) is a selective glycogen synthase kinase 3 (GSK-3) inhibitor with IC50s of 10 nM and 6.7 nM for GSK-3α and GSK-3β. Laduviglusib trihydrochloride inhibits human GSK-3β with a Ki of 9.8 nM. Laduviglusib trihydrochloride is an activator of Wnt/β-catenin signaling. Laduviglusib trihydrochloride induces autophagy.

Web ID

– T22657

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H20Cl5N8

References

– Ring DB, et al. Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes. 2003 Mar;52(3):588-95.

CAS Number

– 1782235-14-6

Molecular Weight

– C22H20Cl5N8

Compound Purity

– 0.9903

SMILES

– Cl.Cl.Cl.Cc1cnc([nH]1)-c1cnc(NCCNc2ccc(cn2)C#N)nc1-c1ccc(Cl)cc1Cl

Target

– Others

Pathway

– Stem Cells|||PI3K/Akt/mTOR signaling|||Cytoskeletal Signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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