3PO
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3PO

SKU T22223-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 83 CAD through 1,358 CAD

Products Details

Product Description

– 3PO is a small-molecule inhibitor of PFKFB3 (IC50: 22.9 μM), inhibiting the proliferation of several human malignant hematopoietic and adenocarcinoma cell lines (IC50: 1.4-24 μM). It suppresses glucose uptake, and decreases the intracellular concentration of Fru-2,6-BP, lactate, ATP, NAD+, and NADH.

Web ID

– T22223

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C13H10N2O

References

– Clem B, et al. Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth. Mol Cancer Ther. 2008 Jan;7(1):110-20.

CAS Number

– 18550-98-6

Molecular Weight

– C13H10N2O

Compound Purity

– 0.9967

SMILES

– O=C(C=Cc1cccnc1)c1ccncc1

Pathway

– Metabolism|||Autophagy

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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