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CID 2745687
Price range: 54 CAD through 1,075 CAD
Products Details
Product Description
– CID 2745687 is a moderately potent, concentration-dependent antagonist at human GPR35 with pIC50 = 6.70. CID 2745687 cannot effectively antagonize the agonist effects of either Zaprinast or Cromolyn disodium at rodent ortholog of GPR35 in vitro[1]. However, CID 2745687 can reverse lodoxamide-mediated anti-fibrotic effects in mice in vivo[2].
Web ID
– T21874
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C17H19F2N5O2S
References
– Jenkins L , Harries N , Lappin J E , et al. Antagonists of GPR35 display high species ortholog selectivity and varying modes of action[J]. Journal of Pharmacology & Experimental Therapeutics, 2012, 343(3):683-695.
CAS Number
– 264233-05-8
Molecular Weight
– C17H19F2N5O2S
Compound Purity
– 0.9911
SMILES
– COC(=O)c1cnn(c1C=NNC(=S)NC(C)(C)C)-c1ccc(F)cc1F
Pathway
– Endocrinology/Hormones|||GPCR/G Protein
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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