AAL-993
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AAL-993

SKU T21593-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 61 CAD through 2,288 CAD

Products Details

Product Description

– AAL-993 is a potent VEGFR inhibitor with IC50s of 130 nM, 23 nM and 18 nM for VEGFR1, VEGFR2 and VEGFR3, respectively. AAL993 has a weak inhibitory effect on other tyrosine kinases. AAL993 also shows potent antiangiogenic and antitumor activities.

Web ID

– T21593

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H16F3N3O

References

– Hyun Seung Ban, et al. Suppression of hypoxia-induced HIF-1alpha accumulation by VEGFR inhibitors: Different profiles of AAL993 versus SU5416 and KRN633. Cancer Lett. 2010 Oct 1;296(1):17-26.

CAS Number

– 269390-77-4

Molecular Weight

– C20H16F3N3O

Compound Purity

– 0.9906

SMILES

– FC(F)(F)c1cccc(NC(=O)c2ccccc2NCc2ccncc2)c1

Target

– ADC Linker

Pathway

– Tyrosine Kinase/Adaptors|||Angiogenesis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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