PC Mal-NHS carbonate ester

Name: PC Mal-NHS carbonate ester | Research Reagent | Immunomart
Brand: TargetMol
SKU: T18522-100 mg

SKU T18522-100 mg Category PROTAC Brand: TargetMol

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– PC Mal-NHS carbonate ester is a cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1]. This chemical compound facilitates drug-antibody conjugation, enabling targeted delivery and enhanced therapeutic efficacy. Its unique carbonate ester structure allows efficient cleavage in the targeted environment, ensuring controlled drug payload release, highlighting its significance in innovative and targeted cancer therapies.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T18522

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H26N4O12

References

– Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

CAS Number

– 1408057-91-9

Molecular Weight

– C24H26N4O12

SMILES

– O=C(ON1C(=O)CCC1=O)OC(C2=CC(OC)=C(OCCCC(=O)NCCN3C(=O)C=CC3=O)C=C2N(=O)=O)C

Target

– IAP

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.