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Palbociclib-propargyl

Name: Palbociclib-propargyl | Research Reagent — Buy Online | Immunomart
Brand: TargetMol
SKU: T18515-2 mg
Price: 133 CAD
Availability: InStock

SKU T18515-2 mg Category PROTAC Brand: TargetMol

133 CAD

Only 1000 item(s) left in stock.

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– Palbociclib-propargyl, a PROTAC ligand targeting the protein CDK6, connects to the CRBN ligand through a PEG linker to form PROTAC CP-10. CP-10 exhibits a potent DC50 value of 2.1 nM against CDK6[1].

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T18515

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H31N7O2

References

– Su S, et al. Potent and Preferential Degradation of CDK6 via Proteolysis Targeting Chimera Degraders. J Med Chem. 2019 Aug 22;62(16):7575-7582.

CAS Number

– 2366269-23-8

Molecular Weight

– C27H31N7O2

SMILES

– CC(=O)c1c(C)c2cnc(Nc3ccc(cn3)N3CCN(CC#C)CC3)nc2n(C2CCCC2)c1=O

Target

– HSP|||Apoptosis

Pathway

– Others

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.