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Plerixafor octahydrochloride

SKU T1776L-5 mg Category Small Compound Brand: TargetMol

Price range: 67 CAD through 1,309 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– Plerixafor octahydrochloride (JM3100 octahydrochloride) blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting in hematopoietic stem cell (HSC) release from bone marrow and HSC movement into the peripheral circulation. Plerixafor is a bicyclam with hematopoietic stem cell-mobilizing activity.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T1776L

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H62Cl8N8

Citations

– 1. Li Y, Niu M, Zhao A, et al. CXCL12 is involved in α-synuclein-triggered neuroinflammation of Parkinson’s disease. Journal of Neuroinflammation. 2019, 16(1): 1-14 2. Theil F, Kuckhahn A, Hörning A, et al.Repeated CXCR4 Blockade by Plerixafor Attenuates Transplant Vasculopathy in Murine Aortic Allografts.The Journal of Immunology.2024, 213(10): 1542-1552.

References

– Zabel BA, et al. J Immunol. 2009, 183(5), 3204-3211.

CAS Number

– 155148-31-5

Molecular Weight

– C28H62Cl8N8

Compound Purity

– 0.9996

SMILES

– Cl.Cl.Cl.Cl.Cl.Cl.Cl.Cl.C(N1CCCNCCNCCCNCC1)c1ccc(CN2CCCNCCNCCCNCC2)cc1

Target

– Others

Pathway

– Autophagy|||Proteases/Proteasome|||Microbiology/Virology|||GPCR/G Protein|||Immunology/Inflammation

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.