Download Files:

Afatinib Dimaleate

SKU T1773-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 54 CAD through 787 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 g 1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg 500 mg

Clear

Products Details

Product Description

– Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB; EGFR) family, with antineoplastic activity.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T1773

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C32H33ClFN5O11

Citations

– 1. Li C, Sun Y D, Yu G Y, et al. Integrated Omics of Metastatic Colorectal Cancer. Cancer Cell. 2020, 38(5): 734-747. e9 2. Mizuma K, Takashima A, Cubitt B, et al. The Pan-ErbB tyrosine kinase inhibitor afatinib inhibits multiple steps of the mammarenavirus life cycle. Virology. 2022

References

– D Li, et al. Oncogene. 2008, 27(34):4702-4711.

CAS Number

– 850140-73-7

Molecular Weight

– C32H33ClFN5O11

Compound Purity

– 0.9966

SMILES

– OC(=O)C=C/C(O)=O.OC(=O)C=C/C(O)=O.CN(C)CC=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1

Target

– Others

Pathway

– Angiogenesis|||Autophagy|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.