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SB 525334

SKU T1763-5 mg Category Small Compound Brand: TargetMol

Price range: 51 CAD through 536 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– SB-525334 is a potent and selective inhibitor of the TGF-β1R and ALK5 (IC50: 14.3 nM).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T1763

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H21N5

Citations

– 1. Peng H, Shen J, Long X, et al. Local Release of TGF‐β Inhibitor Modulates Tumor‐Associated Neutrophils and Enhances Pancreatic Cancer Response to Combined Irreversible Electroporation and Immunotherapy, Local Release of TGF‐β Inhibitor Modulates Tumor‐Associated Neutrophils and Enhances Pancreatic Cancer Response to Combined Irreversible Electroporation and Immunotherapy. Advanced Science. 2022: 2105240

References

– Grygielko ET, et al. Inhibition of gene markers of fibrosis with a novel inhibitor of transforming growth factor-beta type I receptor kinase in puromycin-induced nephritis. J Pharmacol Exp Ther. 2005 Jun;313(3):943-51.

CAS Number

– 356559-20-1

Molecular Weight

– C21H21N5

Compound Purity

– 0.9986

SMILES

– C(C)(C)(C)C=1NC(=C(N1)C=2N=C(C)C=CC2)C3=CC4=C(C=C3)N=CC=N4

Target

– Others

Pathway

– Angiogenesis|||Stem Cells|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.