Download Files:
Apicidin
478 CAD
Only 1000 item(s) left in stock.
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– Apicidin (OSI 2040) is a histone deacetylase (HDAC) inhibitor with antiparasitic and antiproliferative activity. It attenuates memory deficits, inhibits cell growth and proliferation, and induces apoptosis and autophagy by decreasing Abeta load in APP/PS1 mice, making it a valuable tool for leukemia research.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T14305
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C34H49N5O6
References
– Ahn MY, et al. HDAC inhibitor apicidin suppresses murine oral squamous cell carcinoma cell growth in vitro and in vivo via inhibiting HDAC8 expression. Oncol Lett. 2018 Nov;16(5):6552-6560.
CAS Number
– 183506-66-3
Molecular Weight
– C34H49N5O6
Compound Purity
– 0.9993
SMILES
– [H][C@]12CCCCN1C(=O)[C@@]([H])(NC(=O)[C@H](Cc1cn(OC)c3ccccc13)NC(=O)[C@H](CCCCCC(=O)CC)NC2=O)[C@@H](C)CC
Target
– Others
Pathway
– Apoptosis|||Chromatin/Epigenetic|||Autophagy|||DNA Damage/DNA Repair
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
Proudly representing
150+ years of combined research-supply heritage
