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For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– AM-2099 is a selective voltage-gated sodium channel Nav1.7 inhibitor used in pain research.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T14201
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C19H13F3N4O3S2
References
– Marx IE, et al. Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics to Enable in Vivo Target Engagement. ACS Med Chem Lett. 2016 Sep 21;7(12):1062-1067.
CAS Number
– 1443373-17-8
Molecular Weight
– C19H13F3N4O3S2
SMILES
– O=S(=O)(NC1=NC=CS1)C=2C=CC=3C(=NC=NC3C=4C=CC(=CC4OC)C(F)(F)F)C2
Target
– STAT|||PI3K|||Caspase|||Akt|||IL Receptor|||mTOR|||Bcl-2 Family|||p38 MAPK|||JAK|||JNK|||TNF|||ERK|||NF-κB
Pathway
– Membrane transporter/Ion channel
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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