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Semustine

$172$758

Products Details

Product Description

– Semustine is a DNA alkylator, binds to DNA, and acts as a cancer chemotherapeutic agent[1].

Web ID

– HY-13747

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C10H18ClN3O2

References

– [1]Agarwal S, et al. Molecular modeling and spectroscopic studies of semustine binding with DNA and its comparison with lomustine-DNA adduct formation. J Biomol Struct Dyn. 2015;33(8):1653-68.

CAS Number

– 13909-09-6

Molecular Weight

– 247.72

Compound Purity

– 98.0

SMILES

– O=C(NC1CCC(C)CC1)N(CCCl)N=O

Clinical Information

– Phase 3

Research Area

– Cancer

Solubility

– DMSO : 100 mg/mL (ultrasonic)|Ethanol : 50 mg/mL (ultrasonic)

Target

– DNA Alkylator/Crosslinker

Pathway

– Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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