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Rodatristat ethyl
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– Rodatristat ethyl (KAR5585) is a groundbreaking, orally active, and potent inhibitor of tryptophan hydroxylase 1 (TPH1) that significantly reduces 5-hydroxytryptamine (5-HT) levels and decreases pulmonary arterial hypertension (PAH) at low concentrations.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T16779
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C29H31ClF3N5O3
References
– Alice Melão, MSc. Early Results on Rodatristat Ethyl Support Launch of Phase 2 Trial in PAH Patients. FEBRUARY 4, 2019.
CAS Number
– 1673571-51-1
Molecular Weight
– C29H31ClF3N5O3
SMILES
– C(OCC)(=O)[C@@H]1CC2(CCN(CC2)C=3C=C(O[C@@H](C(F)(F)F)C4=C(C=C(Cl)C=C4)C5=CC=CC=C5)N=C(N)N3)CN1
Target
– Others
Pathway
– GPCR/G Protein|||Neuroscience|||Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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