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Amlodipine
Price range: 48 CAD through 270 CAD
Products Details
Product Description
– Amlodipine (UK-48340) is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties.
Web ID
– T1385
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H25ClN2O5
Citations
– 1. Cheng S, Jin P, Li H, et al. Evaluation of CML TKI Induced Cardiovascular Toxicity and Development of Potential Rescue Strategies in a Zebrafish Model. Frontiers in Pharmacology. 2021: 2866.
2. Pan X, Li R, Guo H, et al. Dihydropyridine Calcium Channel Blockers Suppress the Transcription of PD-L1 by Inhibiting the Activation of STAT1. Frontiers in Pharmacology. 2021 Jan 13;11:539261. doi: 10.3389/fphar.2020.539261. eCollection 2020.
3. Ding L, Guo H, Zhang J, et al.Zosuquidar Promotes Antitumor Immunity by Inducing Autophagic Degradation of PD‐L1.Advanced Science.2024: 2400340.
References
– Zhang X, et al. Circulation, 1998, 97(6), 576-580.
CAS Number
– 88150-42-9
Molecular Weight
– C20H25ClN2O5
Compound Purity
– 0.9985
SMILES
– OS(=O)(=O)C1=CC=CC=C1.CCOC(=O)C1=C(COCCN)NC(C)=C(C1C1=CC=CC=C1Cl)C(=O)OC
Target
– NF-κB|||Calcium Channel|||Endogenous Metabolite|||Cytochromes P450|||COX
Pathway
– Membrane transporter/Ion channel|||Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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