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Phenoxodiol

SKU T16522-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 96 CAD through 382 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mg 1 mL * 10 mM (in DMSO)10 mg 5 mg 50 mg

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Products Details

Product Description

– Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP) expression, and sensitizes the cancer cells to Fas-mediated apoptosis. Phenoxodiol induces cell cycle arrest in the G1/S phase of the cell cycle and upregulates p21WAF1 via a p53 independent manner. Phenoxodiol also inhibits DNA topoisomerase II.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T16522

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H12O3

References

– Mahoney S, et al. The effects of phenoxodiol on the cell cycle of prostate cancer cell lines. Cancer Cell Int. 2014 Nov 8;14(1):110.

CAS Number

– 81267-65-4

Molecular Weight

– C15H12O3

Compound Purity

– 0.9807

SMILES

– Oc1ccc(cc1)C1=Cc2ccc(O)cc2OC1

Target

– Drug-Linker Conjugates for ADC

Pathway

– Proteases/Proteasome|||Apoptosis|||DNA Damage/DNA Repair

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.