PF-04937319

SKU T16479-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 61 CAD through 1,368 CAD

Products Details

Product Description

– PF-04937319 is an activator of glucokinase (EC50 =154.4  μM). PF-04937319 maintains glucose-lowering efficacy while mitigating the risk of hypoglycemia observed with many other glucokinase activators. PF-04937319 can be used in research on the treatment of type 2 diabetes mellitus.

Web ID

– T16479

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H20N6O4

References

– Dzyurkevich MS, et al. Pyridoxine dipharmacophore derivatives as potent glucokinase activators for the treatment of type 2 diabetes mellitus. Sci Rep. 2017 Nov 22;7(1):16072.

CAS Number

– 1245603-92-2

Molecular Weight

– C22H20N6O4

Compound Purity

– 0.9861

SMILES

– CN(C)C(=O)c1ncc(Oc2cc(cc3oc(C)cc23)C(=O)Nc2cnc(C)cn2)cn1

Target

– NF-κB|||Estrogen Receptor/ERR|||STAT|||Antibacterial

Pathway

– Metabolism

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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