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Imatinib Mesylate

SKU T1621-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 80 CAD through 131 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)200 mg 500 mg

Clear

Products Details

Product Description

– Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR, respectively).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T1621

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H31N7O·CH4SO3

Citations

– 1. Hu X, Ye K, Bo S, et al.Monitoring imatinib decreasing pericyte coverage and HIF-1α level in a colorectal cancer model by an ultrahigh-field multiparametric MRI approach.Journal of Translational Medicine.2024, 22(1): 712. 2. Zhao Q, Xing F, Tao Y, et al. Xiaozhang Tie Improves Intestinal Motility in Rats With Cirrhotic Ascites by Regulating the Stem Cell Factor/c-kit Pathway in Interstitial Cells of Cajal. Frontiers in Pharmacology. 2020, 11.

References

– Gobin B, et al. Imatinib mesylate exerts anti-proliferative effects on osteosarcoma cells and inhibits the tumour growth in immunocompetent murine models. PLoS One. 2014 Mar 5;9(3):e90795.

CAS Number

– 220127-57-1

Molecular Weight

– C29H31N7O·CH4SO3

Compound Purity

– 0.9997

SMILES

– CS(O)(=O)=O.CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1

Target

– Others

Pathway

– Angiogenesis|||Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||Autophagy

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.