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MS4078

SKU T16153-1 mL * 10 mM (in DMSO) Category PROTAC Brand: TargetMol

Price range: 70 CAD through 1,093 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– MS4078 is an inhibitor and aplastic lymphoma kinase (ALK) PROTAC (degrader) based on Cereblon ligand, with a Kd of 19 nM for binding affinity to ALK.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T16153

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C45H52ClN9O8S

References

– Zhang C, et al. Proteolysis Targeting Chimeras (PROTACs) of Anaplastic Lymphoma Kinase (ALK). Eur J Med Chem. 2018 May 10;151:304-314.

CAS Number

– 2229036-62-6

Molecular Weight

– C45H52ClN9O8S

Compound Purity

– 0.9874

SMILES

– O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCNC(CN4CCC(CC4)C5=CC(OC(C)C)=C(NC=6N=C(NC7=C(S(C(C)C)(=O)=O)C=CC=C7)C(Cl)=CN6)C=C5C)=O

Target

– Antifungal

Pathway

– Tyrosine Kinase/Adaptors|||PROTAC|||Angiogenesis

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.