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Clinofibrate
$50 – $350
Products Details
Product Description
– Clinofibrate (S-8527) is a hypelipidemic agent and a HMG-CoA reductase inhibitor.
Web ID
– HY-13528
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C28H36O6
References
– [1]Okazaki M, et al. Effects of clinofibrate on plasma fibrinogen level in high fructose diet-induced hyperlipidemic rats. In Vivo. 1994 Nov-Dec;8(6):1057-61.|[2]Shirai K, et al. Effect of clinofibrate on lipid metabolism of aorta in atherosclerotic rats. Artery. 1983;12(3):145-55.|[3]Suzuki K, et al. Effects of S-8527 (1,1-bis4′-(1″-carboxy’1″-methylpropoxy)-phenyl)-cyclohexane), a new hypolipidemic compound, on triglyceride metablolism in rats. Biochem Pharmacol. 1975 Jun 15;24(11-12):1203-7.|[4]Suzuki K, et al. Hypolipidemic effect of a new aryloxy compound, S-8527, in experimental animals. Jpn J Pharmacol. 1974 Jun;24(3):407-14.
CAS Number
– 30299-08-2
Molecular Weight
– 468.58
Compound Purity
– 99.87
SMILES
– CCC(OC1=CC=C(C2(C3=CC=C(OC(CC)(C)C(O)=O)C=C3)CCCCC2)C=C1)(C)C(O)=O
Clinical Information
– Launched
Research Area
– Metabolic Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic;warming;heat to 80°C)
Target
– Autophagy;HMG-CoA Reductase (HMGCR)
Pathway
– Autophagy;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
