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Umibecestat
Price range: 280 CAD through 2,640 CAD
Products Details
Product Description
– Umibecestat is an inhibitor of beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1), with IC50s of 11 nM and 10 nM for human BACE-1 and mouse BACE-1, respectively. Umibecestat can be used for the research of alzheimer’s disease.
Web ID
– T13253
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C19H15ClF7N5O2
References
– Neumann U, et al. The BACE-1 inhibitor CNP520 for prevention trials in Alzheimer’s disease. EMBO Mol Med. 2018 Nov;10(11). pii: e9316.
CAS Number
– 1387560-01-1
Molecular Weight
– C19H15ClF7N5O2
Compound Purity
– 1
SMILES
– C[C@]1(CO[C@](C)(C(N)=N1)C(F)(F)F)c1nc(NC(=O)c2ncc(cc2Cl)C(F)(F)F)ccc1F
Target
– Others
Pathway
– Neuroscience
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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