CLZ-8

SKU T16030-1 mg Category Brand:

69 CAD

Only 1000 item(s) left in stock.
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– CLZ-8 (Mcl1-IN-8) is an orally active inhibitor of Mcl-1-PUMA (p53 up-regulated mediator of apoptosis) with radioprotective properties.CLZ-8 ameliorates radiation-induced HUVEC cell damage and reduces apoptosis counts, and inhibits radiation-induced overexpression of PUMA.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T16030

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H23N3O2S

References

– Liu J, et al. Targeting the apoptotic Mcl-1-PUMA interface with a dual-acting compound. Oncotarget. 2017 Apr 20;8(33):54236-54242.

CAS Number

– 678158-55-9

Molecular Weight

– C22H23N3O2S

Compound Purity

– 0.9985

SMILES

– OCCN1CCN(CC1)C1=NC(=O)C(S1)=Cc1ccc(cc1)-c1ccccc1

Target

– Others

Pathway

– Apoptosis

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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For Research Use Only. All Immunomart products are sold strictly for laboratory research use only (RUO). Not for human or veterinary consumption, therapeutic, or diagnostic use.