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Manumycin A

SKU T16011-1 mg Category Natural Product Brand: TargetMol

Price range: 445 CAD through 1,579 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 5 mg

Clear

Products Details

Product Description

– Manumycin A is an antibiotic with anticancer activity and is a mammalian thioredoxin reductase-1 (TrxR-1) inhibitor.Manumycin A inhibits the production of IL-1β, IL-6, and IL-8 in TNF alpha-stimulated THP-1 cells and peripheral blood mononuclear cells in a dose-dependent manner, inducing apoptosis.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T16011

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C31H38N2O7

References

– Hara M, et al. Identification of Ras farnesyltransferase inhibitors by microbial screening. Proc Natl Acad Sci U S A. 1993 Mar 15;90(6):2281-5.

CAS Number

– 52665-74-4

Molecular Weight

– C31H38N2O7

SMILES

– [H][C@]12O[C@@]1([H])[C@](O)(C=CC=CC=CC(=O)NC1=C(O)CCC1=O)C=C(NC(=O)C(C)=CC(C)=C[C@H](C)CCCC)C2=O

Target

– Others

Pathway

– Apoptosis

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.