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Products Details
Product Description
– PF-06733804 is a potent inhibitor of pan-Trk in cell-based assays (IC50s: 8.4 nM, 6.2 nM, and 2.2 nM for TrkA, TrkB, and TrkC) with anti-hyperalgesic effect.
Web ID
– T13207
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H19F5N4O4
References
– Bagal SK, et al. Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain. J Med Chem. 2018 Aug 9;61(15):6779-6800.
CAS Number
– 1873373-33-1
Molecular Weight
– C20H19F5N4O4
SMILES
– O([C@H]1CN(C(CC2=CC=C(OC(F)(F)F)C=C2)=O)CC1(F)F)C=3C=C(C(NC)=O)C=NC3N
Target
– Others
Pathway
– Tyrosine Kinase/Adaptors
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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