KDM5-C70
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KDM5-C70

SKU T15648-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 59 CAD through 1,808 CAD

Products Details

Product Description

– KDM5-C70 is an ethyl ester derivative of KDM5-C49 and functions as an effective, cell-permeable, pan-KDM5 histone demethylase inhibitor. It exhibits an antiproliferative effect in myeloma cells and induces a genome-wide elevation of H3K4me3 levels.

Web ID

– T15648

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H28N4O3

Citations

– 1. Xia L, Zheng Z, Liu J, et al. Targeting triple-negative breast cancer with combination therapy of EGFR CAR T cells and CDK7 inhibition. Cancer Immunology Research. 2021, 9(6): 707-722.

References

– Johansson C, et al. Structural analysis of human KDM5B guides histone demethylase inhibitor development. Nat Chem Biol. 2016 Jul;12(7):539-45.

CAS Number

– 1596348-32-1

Molecular Weight

– C17H28N4O3

Compound Purity

– 99.864

SMILES

– CCOC(=O)c1ccnc(CNCC(=O)N(CC)CCN(C)C)c1

Target

– Others

Pathway

– Chromatin/Epigenetic

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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