Download Files:
JNJ-38877618
Price range: 91 CAD through 1,856 CAD
Products Details
Product Description
– JNJ-38877618 (OMO-1) is an effective and highly selective inhibitor of Met kinase (IC50s: 2 and 3 nM for wild type and mutant Met, respectively).
Web ID
– T15617
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H12F2N6
References
– Libouban M, et al. OMO-1, a potent, highly selective, orally bioavailable, Met kinase inhibitor with a favorable preclinical toxicity profile, shows both monotherapy activity, against Met pathway-driven tumors, and EGFR TKI combination activity in acquired resistance models [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2018; 2018 Apr 14-18; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2018;78(13 Suppl):Abstract nr 4791.
CAS Number
– 943540-74-7
Molecular Weight
– C20H12F2N6
Compound Purity
– 0.9952
SMILES
– FC(F)(c1nnc2ccc(nn12)-c1ccncc1)c1ccc2ncccc2c1
Target
– Others
Pathway
– Tyrosine Kinase/Adaptors
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
1000 in stock
