Download Files:

GSK256073

SKU T15432-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 107 CAD through 1,550 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

Clear

Products Details

Product Description

– GSK256073 is an orally active GPR109A agonist. GSK256073 also is a long-lasting and non-flushing HCA2 (hydroxy-carboxylic acid receptor 2) full agonist (pEC50: 7.5). GSK256073 acutely improves glucose homeostasis via inhibition of lipolysis.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T15432

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C10H13ClN4O2

Citations

– 1. Zhu S, Yuan Q, Li X, et al.Molecular recognition of niacin and lipid-lowering drugs by the human hydroxycarboxylic acid receptor 2.Cell Reports.2023, 42(11). 2. Peroumal D, Jawale C V, Choi W, et al.The survival of B cells is compromised in kidney disease.Nature Communications.2024, 15(1): 1-19.

References

– Dobbins RL, et al. GSK256073, a selective agonist of G-protein coupled receptor 109A (GPR109A) reduces serum glucose in subjects with type 2 diabetes mellitus.Diabetes Obes Metab. 2013 Nov;15(11):1013-21.

CAS Number

– 862892-90-8

Molecular Weight

– C10H13ClN4O2

Compound Purity

– 0.9803

SMILES

– CCCCCn1c2nc(Cl)[nH]c2c(=O)[nH]c1=O

Target

– ADC Linker|||AChR

Pathway

– GPCR/G Protein|||Endocrinology/Hormones

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.