T025
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T025

SKU T13058-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 234 CAD through 5,264 CAD

Products Details

Product Description

– T025 is a pan CLK inhibitor with Kds of 4.8, 0.096, 6.5, 0.61, and 0.074 nM for CLK1-4, respectively. T025 displays anti-proliferative activities with IC50s of 30-300 nM in hematological and solid cancer cell lines. T025 can be used in studies about MYC-driven diseases.

Web ID

– T13058

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H18N8

References

– Iwai K, et al. Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability. EMBO Mol Med. 2018 Jun;10(6). pii: e8289.

CAS Number

– 2407433-00-3

Molecular Weight

– C21H18N8

Compound Purity

– 0.9808

SMILES

– CNc1nc(NCc2ncccn2)c2c(c[nH]c2n1)-c1ccc2ncccc2c1

Target

– Others

Pathway

– Cell Cycle/Checkpoint

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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