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G-744

SKU T15365-25 mg Category Small Compound Brand: TargetMol

Price range: 5,072 CAD through 9,280 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

100 mg 25 mg 50 mg

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Products Details

Product Description

– G-744 is a selective and orally active inhibitor of Btk (IC50: 2 nM). G-744 is well-tolerated, metabolically stable. It also has an efficacious to treat arthritis.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T15365

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H29N5O3S

References

– Wang X, et al. Discovery of Potent and Selective Tricyclic Inhibitors of Bruton’s Tyrosine Kinase with Improved Druglike Properties. ACS Med Chem Lett. 2017 May 3;8(6):608-613.

CAS Number

– 1346669-54-2

Molecular Weight

– C29H29N5O3S

SMILES

– O=C1C2=C(C3=C(S2)CC(C)(C)C3)CCN1C4=C(CO)C(=CC=C4)C=5C=C(NC=6C=CN=CN6)C(=O)N(C)C5

Target

– Others

Pathway

– Angiogenesis|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.