FX-11
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FX-11

SKU T15362-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 66 CAD through 832 CAD

Products Details

Product Description

– FX-11 (LDHA Inhibitor FX11) is A potent, selective and competitive specific inhibitor of lactate dehydrogenase A (LDHA) with a Ki of 8 μM. FX-11 can activate PKM2 (pyruvate kinase M2). FX-11 can reduce ATP levels, induce oxidative stress and ROS production, and cause cell death. FX-11 appeared antitumor activity during xenotransplantation of lymphoma and pancreatic cancer.

Web ID

– T15362

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H22O4

References

– Le A, et al. Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression. Proc Natl Acad Sci U S A. 2010;107(5):2037-204

CAS Number

– 213971-34-7

Molecular Weight

– C22H22O4

Compound Purity

– 0.9895

SMILES

– CCCc1c(O)c(O)c(C(O)=O)c2cc(Cc3ccccc3)c(C)cc12

Target

– Others

Pathway

– Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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