Fenobam
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Fenobam

SKU T15275-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 837 CAD

Products Details

Product Description

– Fenobam shows inverse agonist activity which blocks the mGlu5 receptor basal activity(IC50: 84 nM). Fenobam has anxiolytic activity. Fenobam is a selective and non-competitive mGluR5 antagonist acting at an allosteric modulatory site (Kd values are 54 and 31 nM for rat and human recombinant mGlu5 receptors, respectively).

Web ID

– T15275

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C11H11ClN4O2

References

– Porter RH, et al. Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity. J Pharmacol Exp Ther. 2005 Nov;315(2):711-21.

CAS Number

– 57653-26-6

Molecular Weight

– C11H11ClN4O2

Compound Purity

– 0.9993

SMILES

– CN1CC(=O)N=C1NC(=O)Nc1cccc(Cl)c1

Target

– HIV Protease|||CCR

Pathway

– Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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