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Denifanstat

SKU T15271-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 133 CAD through 3,568 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– Denifanstat (FASN-IN-2) is a fatty acid synthase (FASN) inhibitor (IC50=0.052 μM, EC50=0.072 μM) with selective and oral activity. Denifanstat has been used in studies of steatohepatitis.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T15271

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H29N5O

Citations

– 1. Lu X, Fong K, Gritsina G, et al. HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer. Nature Genetics. 2022-54(5)P670–683 2. Targeting FASN enhances cisplatin sensitivity via SLC7A12-mediated ferroptosis in cervical cancer

References

– Johan D., et al. Heterocyclic modulators of lipid synthesis. WO2012122391A1.

CAS Number

– 1399177-37-7

Molecular Weight

– C27H29N5O

Compound Purity

– 0.9944

SMILES

– Cc1n[nH]c(n1)-c1cc(C(=O)N2CCC(CC2)c2ccc(cc2)C#N)c(C)cc1C1CCC1

Target

– Others

Pathway

– Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.