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Products Details
Product Description
– SJB3-019A is a potent, potent and novel ubiquitin-specific protease 1 (USP1) inhibitor, which promotes ID1 degradation and cytotoxicity in K562 cells 5 times more than SJB2-043, with IC50 of 0.0781 μM. SJB3-019A inhibits cell proliferation and causes cell apoptosis.
Web ID
– T12926
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C16H8N2O3
References
– Mistry H, Hsieh G, Buhrlage SJ, et al. Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells. Mol Cancer Ther. 2013;12(12):2651-2662.
CAS Number
– 2070015-29-9
Molecular Weight
– C16H8N2O3
Compound Purity
– 0.9975
SMILES
– O=C1c2nc(oc2C(=O)c2ccccc12)-c1cccnc1
Target
– Others
Pathway
– Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Ubiquitination
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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