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Sigma-1 receptor antagonist 3
Price range: 130 CAD through 1,525 CAD
Products Details
Product Description
– Sigma-1 receptor antagonist 3 is a more potent and selective antagonist of Sigma-1 (σ1) receptor (Ki = 1.14 nM) than σ2 receptor(Ki = 1239 nM). Sigma-1 receptor antagonist 3 inhibits Human Ether-a-go-go-Related Gene (hERG, IC50 = 1.54 μM)
Web ID
– T12912
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C19H23ClFN3O
References
– Lan Y, et al. Synthesis and biological evaluation of novel sigma-1 receptor antagonists based on pyrimidine scaffold as agents for treating neuropathic pain. J Med Chem. 2014 Dec 26;57(24):10404-23.
CAS Number
– 1639220-17-9
Molecular Weight
– C19H23ClFN3O
Compound Purity
– 1
SMILES
– Cc1nc(nc(OCCCN2CCCCC2)c1Cl)-c1ccc(F)cc1
Target
– Others
Pathway
– GPCR/G Protein|||Membrane transporter/Ion channel
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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