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Astemizole

SKU T1278-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 67 CAD through 150 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 25 mg 5 mg

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Products Details

Product Description

– Astemizole (Laridal) is a synthetic piperidinyl-benzimidazol derivative with antiallergic properties, acts as a reversible competitive inhibitor of histamine H1 receptors, with less anticholinergic effects compared to related agents. It is a long-acting, non-sedative antihistaminic used in the treatment of seasonal allergic rhinitis, asthma, allergic conjunctivitis, and chronic idiopathic urticaria.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T1278

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H31FN4O

Citations

– 1. Wang D, Guo Q, Wu Z, et al.Molecular mechanism of antihistamines recognition and regulation of the histamine H1 receptor.Nature Communications.2024, 15(1): 84. 2. Sun X, Wang Y, Yuan F, et al.Gut symbiont-derived sphingosine modulates vector competence in Aedes mosquitoes.Nature Communications.2024, 15(1): 8221. 3. Molecular mechanism of antihistamines recognition and regulation of the histamine H1 receptor

References

– Salata JJ, et al. Circ Res. 1995 Jan;76(1):110-9.

CAS Number

– 68844-77-9

Molecular Weight

– C28H31FN4O

Compound Purity

– 0.9958

SMILES

– C(N1C=2C(N=C1NC3CCN(CCC4=CC=C(OC)C=C4)CC3)=CC=CC2)C5=CC=C(F)C=C5

Target

– Others

Pathway

– Neuroscience|||GPCR/G Protein|||Immunology/Inflammation|||Membrane transporter/Ion channel

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.