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Cyclo(L-Pro-L-Val)
Price range: 62 CAD through 219 CAD
Products Details
Product Description
– Cyclo(L-Pro-L-Val), a 2,5-diketopiperazine extracted from the fruits of Mycobacterium chiliolyticum AZ2 and Mycobacterium leprae, possesses anti-inflammatory activity and virulence activity against phytopathogenic microorganisms (e.g., R. fascians LMG 3605) and inhibits Gram-positive plant pathogens.Cyclo(L-Pro-L-Val) significantly inhibited IKKα phosphorylation and IκBα and NF-κB activation as well as iNOS and COX-2 activation in a concentration Cyclo(L-Pro-L-Val) significantly inhibited the phosphorylation of IKKα, IKKβ, IκBα, and NF-κB, as well as the activation of iNOS and COX-2 in a concentration-dependent manner, and is a potential therapeutic agent for the treatment of inflammation-related diseases.
Web ID
– T125120
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C10H16N2O2
References
– Cimmino A, et al. Isolation of 2,5-diketopiperazines from Lysobacter capsici AZ78 with activity against Rhodococcus fascians. Nat Prod Res. 2021;35(23):4969-4977.
CAS Number
– 2854-40-2
Molecular Weight
– C10H16N2O2
Compound Purity
– 0.9818
SMILES
– CC(C)[C@@H]1NC(=O)[C@@H]2CCCN2C1=O
Target
– PI3K
Pathway
– Immunology/Inflammation|||NF-κB|||Microbiology/Virology|||Neuroscience
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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