Uzansertib phosphate
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Uzansertib phosphate

SKU T12477-1 mg Category Brand:

Price range: 142 CAD through 1,952 CAD

Products Details

Product Description

– Uzansertib phosphate (INCB053914 phosphate) is an orally active, ATP-competitive inhibitor of pan-PIM kinase(PIM1, PIM2, PIM3 with IC50s of 0.24 nM, 30 nM, 0.12 nM , respectively).

Web ID

– T12477

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H29F3N5O7P

References

– Koblish H, et al. Preclinical characterization of INCB053914, a novel pan-PIM kinase inhibitor, alone and in combination with anticancer agents, in models of hematologic malignancies. PLoS One. 2018 Jun 21;13(6):e0199108.

CAS Number

– 2088852-47-3

Molecular Weight

– C26H29F3N5O7P

Compound Purity

– 0.9985

SMILES

– O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=CN=C4C(CC[C@H]4O)=C3N5C[C@@H](N)[C@H](O)[C@@H](C)C5.O=P(O)(O)O

Target

– Parasite

Pathway

– Chromatin/Epigenetic|||JAK/STAT signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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