Download Files:

NF-56-EJ40 hydrochloride

SKU T12216L-5 mg Category Small Compound Brand: TargetMol

Price range: 80 CAD through 690 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

Clear

Products Details

Product Description

– NF-56-EJ40 hydrochloride is a potent, high-affinity, and highly selective human SUCNR1 (GPR91) antagonist with an IC50 of 25 nM and a Ki of 33 nM, and shows almost no activity towards rat SUCNR1. NF-56-EJ40 hydrochloride has high affinity for humanized rat SUCNR1 with a Ki value of 17.4 nM.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T12216L

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H31Cl2N3O3

References

– Haffke M, et al. Structural basis of species-selective antagonist binding to the succinate receptor. Nature. 2019 Oct;574(7779):581-585.

CAS Number

– 2728500-80-7

Molecular Weight

– C27H31Cl2N3O3

Compound Purity

– 0.9702

SMILES

– O=C(CC1=C(NC(C2=CC=CC(C3=CC=C(CN4CCN(CC4)C)C=C3)=C2)=O)C=CC=C1)O.Cl.Cl

Pathway

– GPCR/G Protein

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.