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Products Details
Product Description
– MG-277 is a molecular glue compound transformed from PROTAC degradation agent, MG-277 potently inhibits tumor cell growth in a p53-independent manner.
Web ID
– T12027
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C41H42Cl2FN5O5
References
– Yang J, et al. Simple Structural Modifications Converting a Bona fide MDM2 PROTAC Degrader into a Molecular Glue Molecule: A Cautionary Tale in the Design of PROTAC Degraders. J Med Chem. 2019 Oct 21.
Molecular Weight
– C41H42Cl2FN5O5
SMILES
– O=C(NCCCCCC1=CC=CC2=C1CN(C2=O)C(C(N3)=O)CCC3=O)[C@@H]4NC5(CCCCC5)[C@@]6(C(NC7=C6C=CC(Cl)=C7)=O)[C@H]4C8=CC=CC(Cl)=C8F
Target
– Others
Pathway
– Apoptosis|||PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
