MBM-17S

SKU T11959-25 mg Category Small Compound Brand: TargetMol

Price range: 2,672 CAD through 4,480 CAD

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Product Description

– MBM-17S, a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 3 nM, effectively inhibits cancer cell proliferation by inducing cell cycle arrest and apoptosis. It demonstrates antitumor activities without evident toxicity to mice.

Web ID

– T11959

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C36H40N6O10

References

– Xi JB, et al. Structure-based design and synthesis of imidazo[1,2-a]pyridine derivatives as novel and potent Nek2 inhibitors with in vitro and in vivo antitumor activities. Eur J Med Chem. 2017 Jan 27;126:1083-1106.

CAS Number

– 2083621-91-2

Molecular Weight

– C36H40N6O10

SMILES

– O=C(CCC(O)=O)O.O=C(C1=C(OCC2=CC=CC=C2)C=C(C3=CN=C4C=C(C5=CN(CCN(C)C)N=C5)C=CN43)C=C1)N.O=C(CCC(O)=O)O

Target

– Apoptosis|||DNA Methyltransferase

Pathway

– Cell Cycle/Checkpoint|||Chromatin/Epigenetic

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

MBM-17S

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