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Products Details
Product Description
– LY3020371 hydrochloride exerts an antidepressant-like signature in vivo. LY3020371 hydrochloride is a potent, selective metabotropic glutamate 2/3 receptor (mGlu2/3) antagonist with Ki of 5.3 and 2.5 nM, potently blocks cAMP formation with IC50 of 16.2 nM.
Web ID
– T11911
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C15H16ClF2NO5S
References
– Witkin JM, et al. In vitro pharmacological and rat pharmacokinetic characterization of LY3020371, a potent and selective mGlu2/3 receptor antagonist. Neuropharmacology. 2017 Mar 15;115:100-114.
CAS Number
– 1377615-44-5
Molecular Weight
– C15H16ClF2NO5S
SMILES
– Cl.[H][C@]12[C@H](C(O)=O)[C@@]1([H])[C@@](N)([C@H](CSc1ccc(F)c(F)c1)[C@H]2O)C(O)=O
Target
– Apoptosis
Pathway
– Neuroscience
Product type
– Small Compound
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