CgoaEGY7S5CEErz6AAAAAEu7nII087- Immunomart

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JHU395

SKU T11717-1 mg Category Small Compound Brand: TargetMol

Price range: 98 CAD through 2,496 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– JHU395 is an orally-bioavailable prodrug of a lipophilic glutamine antagonist (GA), 6-diazo-5-oxo-L-norleucine (DON). It demonstrates delivery of DON to malignant peripheral nerve sheath tumor (MPNST) both in vitro and in vivo, resulting in significant antitumor activity in MPNST. Additionally, JHU395 exhibits plasma stability.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T11717

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H29N3O7

References

– Lemberg KM, et al. The novel glutamine antagonist prodrug JHU395 has antitumor activity in malignant peripheralnerve sheath tumor. Mol Cancer Ther. 2020;19(2):397-408.

CAS Number

– 2079938-92-2

Molecular Weight

– C22H29N3O7

Compound Purity

– 0.9915

SMILES

– C(OC(C(C)(C)C)=O)(OC(N[C@H](C(OC(C)C)=O)CCC(C=[N+]=[N-])=O)=O)C1=CC=CC=C1

Target

– Others

Pathway

– Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.