GSK840
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GSK840

SKU T11501-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 51 CAD through 477 CAD

Products Details

Product Description

– GSK840 (GSK’840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor that binds to the RIP3 kinase domain (IC50: 0.9 nM) and inhibits kinase activity (IC50: 0.3 nM).

Web ID

– T11501

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H23N3O3

Citations

– 1. Tu X, Zou Z, Li J, et al.Artificial intelligence-enabled discovery of a RIPK3 inhibitor with neuroprotective effects in an acute glaucoma mouse model.Chinese Medical Journal.2024: 10.1097.

References

– Mandal P, et al. RIP3 induces apoptosis independent of pronecrotic kinase activity. Mol Cell. 2014 Nov 20;56(4):481-95.

CAS Number

– 2361146-30-5

Molecular Weight

– C21H23N3O3

Compound Purity

– 0.997

SMILES

– CNC(=O)c1ccc2n(cnc2c1)-c1ccc(CC(=O)OC(C)(C)C)cc1

Target

– Others

Pathway

– Apoptosis|||NF-κB

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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