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Epertinib hydrochloride
Price range: 134 CAD through 3,440 CAD
Products Details
Product Description
– Epertinib hydrochloride (S-22611 hydrochloride) shows potent antitumor activity. Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively.
Web ID
– T11213
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C30H28Cl2FN5O3
References
– Tanaka H, et al. Preclinical antitumor activity of S-222611, an oral reversible tyrosine kinase inhibitor of epidermal growth factor receptor and human epidermal growth factor receptor 2. Cancer Sci. 2014 Aug;105(8):1040-8.
CAS Number
– 2071195-74-7
Molecular Weight
– C30H28Cl2FN5O3
Compound Purity
– 0.9914
SMILES
– Cl.CC#CC(=N/OC[C@H]1COCCN1)c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1
Target
– Antibacterial|||STAT|||Antibiotic
Pathway
– Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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