EB-47
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EB-47

SKU T11143-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 99 CAD through 1,173 CAD

Products Details

Product Description

– EB-47 mimics the substrate NAD+ and extends from the nicotinamide to the adenosine subsite.EB-47, a potent and selective PARP-1/ARTD-1 inhibitor with an IC50 value of 45 nM, shows modest potency against ARTD5 with an IC50 value of 410 nM.

Web ID

– T11143

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H27N9O6

References

– Haikarainen T, et al. Evaluation and Structural Basis for the Inhibition of Tankyrases by PARP Inhibitors.ACS Med Chem Lett. 2013 Nov 20;5(1):18-22.

CAS Number

– 366454-36-6

Molecular Weight

– C24H27N9O6

Compound Purity

– 0.9981

SMILES

– O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](C(=O)N4CCN(CC(NC5=C6C(C(=O)NC6)=CC=C5)=O)CC4)[C@H]1O

Target

– Others

Pathway

– Chromatin/Epigenetic|||DNA Damage/DNA Repair

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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