Darbufelone
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Darbufelone

SKU T10960-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 59 CAD through 1,888 CAD

Products Details

Product Description

– Darbufelone (CI-1004) is a non-competitive dual inhibitor of PGF2α and LTB4. Dabfilon effectively inhibits PGHS-2 with a Ki of 10 μM and IC50s of 0.19 μM and 20 μM for PGHS-2 and PGHS-1.

Web ID

– T10960

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H24N2O2S

References

– Johnson AR, et al. Slow-binding inhibition of human prostaglandin endoperoxide synthase-2 with darbufelone, an isoform-selective antiinflammatory di-tert-butyl phenol. Biochemistry. 2001 Jun 26;40(25):7736-45.

CAS Number

– 139226-28-1

Molecular Weight

– C18H24N2O2S

Compound Purity

– 0.9977

SMILES

– C(C1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1)=C2/C(=O)N=C(N)S2

Target

– STAT

Pathway

– Immunology/Inflammation|||GPCR/G Protein

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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