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CK2/ERK8-IN-1

SKU T10827-5 mg Category Small Compound Brand: TargetMol

48 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

10 mg 5 mg

Clear

Products Details

Product Description

– CK2/ERK8-IN-1 (TMCB) is a dual inhibitor of casein kinase 2 (CK2) (Ki: 0.25 µM) and ERK8 (IC50s: 0.50 μM) with pro-apoptotic efficacy. CK2/ERK8-IN-1 also binds to PIM1, DYRK1A, and HIPK2 (Kis: 8.65 µM, 11.9 µM, and 15.25 µM).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T10827

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C11H9Br4N3O2

References

– Pagano MA, et al. The selectivity of inhibitors of protein kinase CK2: an update. Biochem J. 2008 Nov 1;415(3):353-65.

CAS Number

– 1085822-09-8

Molecular Weight

– C11H9Br4N3O2

Compound Purity

– 0.9882

SMILES

– CN(C)c1nc2c(Br)c(Br)c(Br)c(Br)c2n1CC(O)=O

Target

– Apoptosis

Pathway

– MAPK|||Apoptosis|||Chromatin/Epigenetic|||JAK/STAT signaling|||Metabolism|||Stem Cells|||Tyrosine Kinase/Adaptors|||Cell Cycle/Checkpoint

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.