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Products Details
Product Description
– ARS-1323-alkyne is a switch-II pocket (S-IIP) inhibitor and a conformational specific chemical reporter of KRASG12C nucleotide state in living cells.
Web ID
– T10374
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C28H27ClF2N6O3
References
– Lou K,et al. KRASG12C inhibition produces a driver-limited state revealing collateral dependencies. Sci Signal. 2019 May 28;12(583). pii: eaaw9450.
CAS Number
– 2436544-27-1
Molecular Weight
– C28H27ClF2N6O3
Compound Purity
– 0.99
SMILES
– CN(CC#C)C(=O)CCNc1nc(N2CCN(CC2)C(=O)C=C)c2cc(Cl)c(c(F)c2n1)-c1c(O)cccc1F
Target
– Others
Pathway
– GPCR/G Protein|||MAPK
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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